The NMR spectroscopy of liquid crystalline samples provides uniquely rich information on the structure, conformation and orientational order of the molecules. There are applications to pure liquid crystals, to dissolved molecules, and to biological macromolecules, and the interests of the scientific community which engages in this area of research are not usually well represen-ted at the many, large conferences on the applications of NMR in general, on biological applications, or on liquid crystals. To remedy this neglect and in order to bring together those people interested in the applications of this subject, in 2005 and 2007 two meetings were organized in a lovely location in Tropea Calabria (Italy) with a good participation from such far-flung places as Canada, Armenia, Sweden, Netherlands, Poland, Finland, France, Slovenia, England, and several parts of Italy. Both meetings proved to be very stimulating, and enjoyable (some credit has to be given to the hospitality of the host and to the splendid view offered by the Monastery of Frati Minori – not only the spirit but the flesh too has to be nurtured and taken care of!); therefore the organizers were asked to repeat the experience in 2009, hoping that this conference will become a regular chance to discuss common problems in the application of this fascinating aspect of NMR spectroscopy.