Maria Rosaria Tinè

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Prof. Maria Rosaria Tinè

Associate Professor (Professore Associato)
Address :  Via Moruzzi, 13 - Pisa
Phone :  +39 050 2219268
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Maria Rosaria TINE’, is Associate Professor of Biophysical Chemistry at the Department of Chemistry of the University of Pisa. Actually she gives courses in Physical Chemistry and in Biophysical Chemistry. She is the author of about 100 scientific publications (and 1 patent) on peer-reviewed journals and books in the field of Biophysical Chemistry.


Documenti Consiglio Universitario Nazionale
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Candidatura al CUN


Responsibilities         

• Director of THERMOLAB, Laboratory of Chemical Thermodynamics and Calorimetry at the Department of Chemistry (UNIPI);

• Member of the National University Council; Coordinator of the Research Committee

• Member of the Board of Università di Napoli Federico II

• Italian Representative in the Scientific Board of the European Society of Thermal Analysis and Calorimetry (ESTAC); 

• Member of the Steering Committee of the Tuscan Technology District for Cultural Heritage;

• UNIPI Representative in the Sustainable Housing and Cultural Heritage Tuscan Cluster;

• Past President and Member of the Executive Board of the Italian Association of Calorimetry and Thermal Analysis (AICAT);

• Vice-President of the Tuscan Section of the Italian Chemistry Society (SCI) and member of SCI;

• (2002-2007) President of AICAT and member of the Scientific Board of the Mediterranean Association of Calorimetry and Thermal Analysis (MEDICTA);

• (2010-2012) Treasurer and member of the Council of the Physical Chemical Division of SCI;

• (2013-2015) President of the Ph.D. Course in Biomaterials

• (2010-2012) Deputy President and Coordinator of teaching activities of the Ph.D. School BIOS Biomolecular Sciences (UNIPI) and Member of the Council of the School.

• Member of the American Chemical Society;

• Member of the International Confederation for Thermal Analysis and Calorimetry (ICTAC).


 

Main research fields and subjects      

Her research interests focus on the characterization of physicochemical properties of chemical and biochemical systems and on the thermodynamic kinetic and calorimetric investigation of chemical processes, with a special emphasis on:

Microwave assisted synthesis and physico-chemical characterization of metal nanoparticles such as superparamagnetic nanoparticles based on iron oxides, USPIONs and silver nanoparticles

• Microwave and ultrasound assisted extraction and physico-chemical characterization of essential oils from plants, seeds, peels.

• Physico-chemical characterization of materials based on hallosyte nanotubes bare and loaded with bioactive molecules, nanoparticles, proteins.

• Biophysical chemistry, focusing on thermodynamics, calorimetry and kinetics of molecular interactions, folding, and self-organizing and on physical chemistry of self-assembly systems, for biomedical applications.

• Chemical-physical methods and modelling for the study of the processes of conservation and valorisation of cultural heritage, focusing on ligands (proteins and proteinaceous material, oils, resins) in paints, on their interaction with pigments, and on their degradation.

• Predictive models of the chemical-physical properties and toxicity of substances, in particular of solubility and repartition of organic molecules mono- and poly-functional in different solvents, both by QSAR/QSPR analysis based on group contribution and by a new method based on a recursive neural network able to consider structured domains as input data.

• Thermodynamics and kinetics of the formation of metal complexes in aqueous solution and of their reactivity toward small molecules and substrates, focusing on the synthetic carriers and activators of oxygen and on the interaction of metal receptors with dioxygen and CO. Thermodynamics and kinetics of the interaction of DNA with metal receptors, focusing on the intercalation processes.

• Extraction/recovery of specific metal ions by micellar systems.

• Thermodynamics of organic mixtures and solutions and their properties (free energy, volume and enthalpy in excess). Collaboration with the international program TOM (systematic collection and critical revision of experimental mixing properties) focusing on improvement and parametrization of a quasi-chemical model DISQUAC for the prediction of mixing properties.

• Diffusion and improvement of integrated calorimetric techniques for the characterisation of complex materials. Project of a low cost multimode calorimeter (international patent).

International and National Collaborations

· Prof. H.V. Kehiaian (1986 – 2006), CNRS, Université Paris VII

· Prof. B.H Robinson (2004 – 2008) University of East Anglia;

· Prof. Sonja Nikolic, Institut Ruder Bošković, Università di Zagabria;

· Prof. Zvonko Jaglicic, University of Ljubljana;

· Prof. Leslie Carlyle, Universidade Nova de Lisboa (FCT/UNL);

· Gruppo Chemical Science for the Safeguard of Cultural Heritage (SCiCH)

coordinato dalla Prof. M.P. Colombini, Dipartimento di Chimica e Ch. Ind. Università di Pisa;

· Prof. Angela Agostiano, Università di Bari;

· Dr. Emilia Bramanti – Istituto di Chimica dei Composti Organo Metallici-ICCOM-UOS, CNR di Pisa;

· Dr. Carlo Ferrari, Istituto Nazionale di Ottica del CNR di Pisa;

· Prof. A. Pedone, Dip. di Scienze Chimiche e Geologiche, Università di Modena e Reggio Emilia;

· Dr Stefano Vecchio Ciprioti, Dipartimento di Scienze di Base ed Applicate per l’Ingegneria (S.B.A.I.), Università “La Sapienza” di Roma;

· Prof. Giovanni Vozzi, Dipartimento di Ingegneria dell’Informazione, Università di Pisa;

· Prof. Simone Capaccioli, Dipartimento di Fisica, Università di Pisa;

· Prof. Guido Flamini, Dipartimento di Farmacia, Università di Pisa;

· Prof. Guido Pampaloni, Dipartimento di Chimica e Chimica Industriale, Università di Pisa;

· Prof Valentina Domenici, Dipartimento di Chimica e Chimica Industriale, Università di Pisa;

· Dr. Francesco Pineider, Dipartimento di Chimica e Chimica Industriale, Università di Pisa;

· Prof. Manuela Giovannetti, Dip. di Scienze Agrarie, Alimentari e Agro-ambientali Università di Pisa;

· Dr. Carlo Ferrari, Istituto Nazionale di Ottica del CNR di Pisa;

· Dr. Alessandra Piras, Dipartimento di Scienze Chimiche e Geologiche, Università di Cagliari;

· Prof. Alessio Micheli, Dipartimento di Informatica, Università di Pisa;

· Prof. Roberto Solaro (2005 -2012), Dipartimento di Chimica e Chimica Industriale, Università di Pisa;

· Dr. Susanna Monti, Istituto di Chimica dei Composti Organo Metallici-ICCOM-UOS del CNR di Pisa;

· Prof. A. Schiraldi e D. Fessas – Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche (DISTAM) Università di Milano.


Tinè Maria Rosaria Publications


Teaching      
082CCChimica Fisica 1
182CCChimica Fisica Biologica