Venerdì 6 giugno 2025 - Ore 10:00 - Aula 22
Prof. Thomas Rades
Department of Pharmacy, University of Copenhagen
  Seminario  

Most drug delivery today utilizes solid dosage forms, especially for small molecules. However, the solid state of drugs can take many forms, and increasingly high energy solids are used, with different degrees of disorder, ranging from stable to metastable crystalline forms, to supercooled liquid crystalline forms, to amorphous forms. In this presentation we will initially discuss different solid-state forms and explore their usefulness for drug delivery and then aim to elucidate a better understanding of amorphous forms of the drug molecules themselves, both as a rational basis for the development of ASDs as well as for the exciting opportunity to enable the development of amorphous engineering approaches.

Lunedì 9 giugno 2025 - Ore 10:30 - Aula 32
Seminari di fine anno dei Dottorandi del 37° ciclo della Scuola di Dottorato in Scienze Chimiche e dei Materiali (DSCM)

  Discussione Tesi DSCM  

• Rosaria Lorè
  Total green valorization of paper mill wastes through different approaches in the perspective of circular economy
  Supervisori: Prof.ssa Claudia Antonetti e Prof.ssa Anna Maria Raspolli Galletti

Venerdì 18 luglio 2025 - Aula 21
Seminari di fine anno dei Dottorandi del 36° e 37° ciclo della Scuola di Dottorato in Scienze Chimiche e dei Materiali (DSCM)

  Discussione Tesi DSCM  

• ORE 15:00
  ZAHRAALSADAT YOUSEFNIAYEJAHROMI (37° ciclo)
  "Development of Innovative Electrochemical Biosensors for Bacterial Detection"
  Supervisori: Prof. Fabio Di Francesco e Prof.ssa Arianna Tavanti
• ORE 17:00
  ELENA EREMEEVA (36° ciclo)
  "Development of an Experimental System for Studying Molybdenum-Indium Oxide Based Chemoresistive Sensors in High Humidity Environments"
  Supervisore: Prof. Fabio Di Francesco

Lunedì 15 settembre 2025 - Ore 11:00 - Aula 22
Dr.ssa Francesca Di Turo, recente vincitrice di uno starting grant ERC
  Seminario  

Martedì 16 settembre 2025 - Ore 14:30 - Aula 22
Prof. Matteo Palma - Department of Chemistry, Queen Mary University of London
  Seminario  

The controlled organization of individual molecules and nanostructures with nanoscale accuracy is key for the investigation of nanoscale and single-molecule events in optoelectronic, biosensing and biomimicking platforms. In this regard, we developed different strategies based on the selective functionalization of 0 dimensional (D; Quantum Dots), 1D (carbon nanotubes) and 2D (MoS2) based mixed-dimensional heterostructures towards the development of novel hybrids for single-molecule studies and different technological applications, from photo-responsive devices to nanoscale biosensing chips. We further employ DNA nanostructures as static and dynamic building blocks for the construction of the aforementioned functional nanohybrids, and for the fabrication of biomimetic nanoarrays that permit the multivalent investigation of ligand−receptor molecule interactions in cancer, with nanoscale spatial resolution and single-molecule control.

Venerdì 19 settembre 2025 - EVENTO ANNULLATO
Dott. Marc Mauduit
École Natonale Supérieure de Chimie de Rennes, Rennes Insitute of Chemical Sciences
  Seminario  

In 2007, a new class of carbenes, namely cyclic (alkyl) (amino) carbenes (CAACs), emerged as a competitor to NHCs as ligands for olefin metathesis catalysts. Since then, CAACs have been intensively studied, demonstrating exceptional productivity in ethenolysis processes (Turnover number up to 2.6 million at 100 ppb catalyst loading) while achieving remarkable catalytic performances in a number of other metathesis transformations. Despite these impressive results, the use of CAAC ligands in asymmetric catalysis is still in its infancy. This lecture will present pioneering developments in optically pure CAAC-Ruthenium complexes and their evaluation in asymmetric olefin metathesis. Additionally, thanks to density functional theory models, mechanistic insights highlighting the origin of enantioselectivity will also be discussed.

Venerdì 19 settembre 2025 - Ore 11:30 - Aula Magna
Prof. Rinaldo Poli, Laboratoire de Chimie de Coordination, Toulouse, France
  Seminario  

Homogeneous catalysis has advantages in terms of activities and selectivities, but suffers from poor catalyst recovery and recycle. An interesting approach for catalyst recovery is confinement onto a solid surface (heterogenized homogeneous catalysis) or in a different liquid phase (liquid/liquid biphasic catalysis). In the latter case, water is the most attractive catalyst phase. A large-scale, industrially implemented process based on an aqueous liquid/liquid biphasic protocol is the Rh-catalyzed hydroformylation of light olefins. Extension to higher olefins, however, is hampered by the insufficient olefin solubility in water, which limits mass transport. This problem can be alleviated by anchoring the catalyst in the hydrophobic core of micelles, where the water-insoluble substrates can migrate and accumulate at high concentrations. We have introduced a new catalyst support, which consists of core-crosslinked micelles with a hydrophilic shell and a hydrophobic core where the catalyst is firmly anchored. I’ll present the advantages, pitfalls and improvements of this support. I’ll describe the synthesis and characterization of the organized polymers and their application to aqueous biphasic transformations catalyzed by both molecular metal complexes and metallic nanoparticles

Venerdì 26 settembre 2025 
Dipartimento di Chimica e Chimica Industriale, Università di Pisa
  Evento  

Il Dipartimento di Chimica e Chimica Industriale è lieto di annunciare la nuova edizione del BRIGHT in programma venerdì 26 settembre 2025. L’acronimo BRIGHT significa “Brilliant Researchers Impact on Growth Health and Trust in research” (I ricercatori di talento hanno un impatto sulla crescita, la salute e la fiducia nella ricerca), a simboleggiare l’aspetto positivo dell’attività di ricerca e divulgare un messaggio di fiducia al grande pubblico. Dopo il successo dello scorso anno, con la partecipazione di 1115 studenti, suddivisi per tipologia di scuola, dalla scuola primaria alla scuola secondaria di II grado, in quattro giorni e considerate le richieste sempre crescenti di partecipazione, il Dipartimento di Chimica ha deciso di ampliare ancora di più le attività divulgative e dimostrative del Bright. Quest’ anno quindi, dopo aver concordato con i vari istituti richiedenti la tipologia di attività e le date più consone, i nostri ricercatori e le nostre ricercatrici accoglieranno i bambini delle scuole primarie e gli alunni delle secondarie di primo grado in dipartimento per delle “Giornate della Chimica” durante l’intero anno scolastico. Agli istituti secondari di II grado sarà invece completamente riservata l’intera giornata del 26 settembre, giornata europea BRIGHT, con un programma di stand, esperimenti, dimostrazioni e conferenze.

Lunedì 29 settembre 2025 - Ore 14:30 - Aula 21
Dott. Filippo Giovanni Fabozzi - HechtLab, Department of Chemistry & Center for the Science of Materials Berlin, Humboldt-Universität zu Berlin, Germany
  Seminario  

Surfaces and interfaces are all around us and represent critical zones of interactions where materials meet remarkable changes in physical, chemical, or biological properties, often leading to unique phenomena that are essential to both fundamental processes and advanced technological applications. Scanning Probe Microscopies, including Atomic Force Microscopy (AFM) and Scanning Tunneling Microscopy (STM) stand as primary tools for the visualization of phenomena on crystalline surfaces, thanks to their unprecedented lateral resolution. However, full understanding and control of such processes at the nanoscale remain one of the main challenges in surface science. In this context, the application of STM at the solid-liquid interface emerges not only as an imaging technique for unravelling 2D-nanoarchitectures at the molecular level, but also means to initiate and control chemical and physical processes confined in the second dimension on crystalline surfaces.1 We show how the importance of a rational molecular design influences the supramolecular organization of building blocks, facilitating the formation of a novel class of π-conjugated 2D-polymers known as vinylene-linked Covalent Organic Frameworks.2 Furthermore, we demonstrate how the applied electric field induced by the STM tip can be used to precisely control conformational changes in molecular 2D-crystals, leading to a full control at the nanoscale of molecular Moiré Patterns.3 Finally, a strategy by combining a rational self-assembly with light irradiation to achieve chemical control over photochemical reactions of non-symmetric stilbene derivatives will be briefly introduced. This interdisciplinary journey through the combination of chemistry and physics highlight the pivotal role of the STM in the understanding and manipulation of fundamental phenomena on surfaces, advancing the understanding of nanoscience as the basics of nanotechnology.

Giovedì 2 ottobre 2025 - Ore 14:30 - Aula 21
Prof. Richard Robinson - Materials Science Department, Cornell University
  Seminario  

Magic-sized clusters (MSC) are identical CdS inorganic cores that maintain a closed-shell stability, inhibiting growth processes. Because MSCs are smaller than nanoparticles, they can mimic molecular-level processes, and because of their small size and high organic-ligand/core ratio, MSCs have “softer” inter-particle interactions, with access to a richer phase diagram beyond the classical close packed structures seen with larger particles. I will highlight some remarkable behavior we have recently found, including their ability to undergo a chemically-induced, reversible isomeric transformation between discrete states. These MSCs self-organize into films with hierarchical assembly that spans over seven orders of magnitude in length scale. Meniscus-guided evaporative assembly results in large-scale homochiral domains with anisotropy values (g-factors) near 1.1 and areas surpassing 6 mm2. These g-factors are among the highest reported for all semiconductor particles. Through Mueller matrix polarimetry spatial mapping we unravel the mechanism behind the formation of the self-organized chiral domains. Beyond optical properties, the multiscale self-organization behavior of these MSCs displays similarities to biosystems, providing a new platform for the design and study of materials.